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E Ghigo Selected Research

Insulin-Like Growth Factor I (IGF-1)

5/2022Optimal timing of blood samplings to detect GH inhibition during oral glucose tolerance test.
4/2021Biliary adverse events in acromegaly during somatostatin receptor ligands: predictors of onset and response to ursodeoxycholic acid treatment.
2/2020Untreated adult GH deficiency is not associated with the development of metabolic risk factors: a long-term observational study.
6/2017Pegvisomant in acromegaly: an update.
4/2012Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients.
12/2011The exon 3-deleted growth hormone receptor: molecular and functional characterization and impact on GH/IGF-I axis in physiological and pathological conditions.
3/2010Growth hormone/insulin-like growth factor-I axis in obstructive sleep apnea syndrome: an update.
12/2009Comparison of pegvisomant and long-acting octreotide in patients with acromegaly naïve to radiation and medical therapy.
12/2008Growth hormone/insulin-like growth factor I axis, glucose metabolism, and lypolisis but not leptin show some degree of refractoriness to short-term fasting in acromegaly.
9/2008Update on epidemiology, etiology, and diagnosis of adult growth hormone deficiency.
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E Ghigo Research Topics

Disease

25Obesity
07/2021 - 06/2000
20Acromegaly
10/2022 - 01/2002
10Hypopituitarism (Sheehan's Syndrome)
08/2013 - 01/2000
10Neoplasms (Cancer)
08/2012 - 02/2001
9Anorexia Nervosa
07/2005 - 06/2000
8Starvation
12/2008 - 01/2003
7Pituitary Diseases (Disease, Anterior Pituitary)
08/2021 - 06/2004
6Malnutrition (Nutritional Deficiencies)
07/2021 - 01/2000
6Adrenal Insufficiency (Adrenal Gland Hypofunction)
07/2021 - 07/2000
6Type 2 Diabetes Mellitus (MODY)
04/2021 - 12/2008
5Q Fever (Fever, Q)
12/2009 - 01/2000
5Body Weight (Weight, Body)
08/2008 - 04/2003
5Anorexia
05/2006 - 05/2002
4Dyslipidemias (Dyslipidemia)
11/2014 - 08/2008
4Insulin Resistance
02/2014 - 10/2004
4Hypothyroidism
01/2009 - 06/2002
4Hypoglycemia (Reactive Hypoglycemia)
04/2002 - 10/2000
4Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
03/2002 - 02/2000
3Morbid Obesity
07/2021 - 11/2007
3Obstructive Sleep Apnea
05/2021 - 11/2002
3Cushing Syndrome
12/2020 - 03/2001
3Hypertension (High Blood Pressure)
02/2020 - 08/2008
3Addison Disease (Addison's Disease)
05/2016 - 07/2000
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
08/2012 - 06/2002
3Amenorrhea
12/2009 - 06/2002
3Traumatic Brain Injuries (Traumatic Brain Injury)
09/2008 - 06/2004
3Hyperinsulinism (Hyperinsulinemia)
11/2003 - 04/2002
3Endocarditis
04/2001 - 01/2000
2Gallstones (Gallstone)
04/2021 - 08/2008
2Hypercholesterolemia
02/2020 - 11/2014
2Neuroendocrine Tumors (Neuroendocrine Tumor)
02/2015 - 10/2006
2Hypertriglyceridemia
11/2014 - 08/2013
2Breast Neoplasms (Breast Cancer)
02/2012 - 04/2001
2Hypoxia (Hypoxemia)
03/2010 - 01/2004
2Hyperthyroidism
01/2009 - 01/2003
2Heart Failure
08/2008 - 12/2001
2Pituitary ACTH Hypersecretion
10/2007 - 02/2001
2Feeding and Eating Disorders (Eating Disorder)
07/2005 - 10/2004
2Cachexia
05/2004 - 12/2003
2Abdominal Obesity
01/2004 - 06/2002
2Liver Cirrhosis (Hepatic Cirrhosis)
06/2003 - 06/2002
2Overweight
05/2002 - 06/2000
2Medullary Carcinoma
04/2002 - 04/2000
2Hypersensitivity (Allergy)
04/2002 - 10/2000
2Wounds and Injuries (Trauma)
03/2002 - 02/2002
2Migraine Disorders (Migraine)
05/2001 - 05/2000
2Ischemia
02/2001 - 02/2000
2Combined Pituitary Hormone Deficiency
01/2001 - 01/2000
1Endocrine System Diseases (Endocrine Diseases)
08/2021
1Disruptive, Impulse Control, and Conduct Disorders (Kleptomania)
08/2021

Drug/Important Bio-Agent (IBA)

39Insulin-Like Growth Factor I (IGF-1)IBA
05/2022 - 01/2000
20GhrelinIBA
04/2010 - 04/2001
19Growth Hormone (Somatotropin)IBA
11/2021 - 05/2000
18Insulin (Novolin)FDA Link
02/2014 - 06/2000
17Adrenocorticotropic Hormone (ACTH)FDA Link
07/2021 - 07/2000
13Glucose (Dextrose)FDA LinkGeneric
05/2022 - 06/2000
11Hydrocortisone (Cortisol)FDA LinkGeneric
12/2020 - 10/2000
9Arginine (L-Arginine)FDA Link
12/2009 - 02/2000
8Hormones (Hormone)IBA
03/2010 - 08/2000
7Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
05/2018 - 06/2000
6Peptides (Polypeptides)IBA
12/2013 - 02/2001
6SecretagoguesIBA
10/2006 - 04/2001
5pegvisomantFDA LinkGeneric
05/2018 - 09/2007
5Insulin-Like Growth Factor Binding Protein 3IBA
12/2009 - 09/2000
5Messenger RNA (mRNA)IBA
10/2006 - 12/2000
5Proteins (Proteins, Gene)FDA Link
10/2006 - 01/2000
5hexarelinIBA
03/2002 - 02/2000
4LigandsIBA
10/2022 - 06/2011
4Somatostatin Receptors (Somatostatin Receptor)IBA
10/2022 - 06/2011
4SteroidsIBA
04/2021 - 01/2000
4Biological ProductsIBA
08/2012 - 04/2001
3GlucocorticoidsIBA
05/2016 - 07/2008
3LeptinIBA
12/2008 - 02/2003
3AldosteroneIBA
07/2007 - 10/2000
3ProlactinIBA
04/2006 - 05/2001
3Dehydroepiandrosterone (DHEA)IBA
02/2004 - 01/2000
3Insulin-Like Growth Factor Binding ProteinsIBA
04/2002 - 01/2000
3Nonesterified Fatty Acids (NEFA)IBA
08/2001 - 06/2000
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2001 - 01/2000
2AlbuminsIBA
07/2021 - 02/2002
2MicronutrientsIBA
07/2021 - 01/2000
2Thyroxine (Levothyroxine)FDA LinkGeneric
02/2020 - 01/2009
2LipidsIBA
08/2013 - 08/2008
2Insulin-Like Growth Factor Binding Protein 1IBA
04/2012 - 08/2001
2Metformin (Glucophage)FDA LinkGeneric
02/2012 - 01/2012
2Hypoglycemic Agents (Hypoglycemics)IBA
02/2012 - 01/2012
2Thyroid HormonesIBA
01/2009 - 01/2003
2cortistatinIBA
10/2006 - 04/2002
2Insulin-Like PeptidesIBA
12/2003 - 12/2000
2GonadotropinsIBA
06/2003 - 03/2003
2AutoantibodiesIBA
12/2001 - 07/2000
2Sumatriptan (Imigran)FDA LinkGeneric
05/2001 - 05/2000
2tyrosyl-alanyl-hexarelinIBA
04/2001 - 04/2000
1amsonic acid (DAS)IBA
08/2021

Therapy/Procedure

11Therapeutics
10/2022 - 06/2004
4Radiotherapy
08/2012 - 04/2003
3Drug Therapy (Chemotherapy)
02/2012 - 10/2006
2Bariatric Surgery
07/2021 - 05/2021
2Cholecystectomy
04/2021 - 08/2008
2Cranial Irradiation
09/2008 - 02/2008